Africa cruises offer a unique opportunity to explore one of the world's most diverse and fascinating continents. Whether you want to witness the Great Migration of wildebeest and zebras in the Serengeti, explore the ancient ruins of Egypt, or relax on the stunning beaches of South Africa, an Africa cruise has something for everyone. Many cruises also offer opportunities to spot wildlife such as lions, elephants, and giraffes in their natural habitats. With itineraries ranging from a few days to several weeks, there are plenty of options to suit any traveler's preferences and budget. Some cruises even offer exclusive experiences such as hot air balloon rides over the African savanna or visits to remote villages to learn about traditional cultures. Whatever your interests, an Africa cruise promises to be a journey of discovery and adventure.

Africa Itineraries

31 Nights

Cape Town to Lisbon

Departure Date
12 Apr 25
Cruise LineCrystal
Cruise TypeOcean
ShipCrystal Symphony
RegionAfrica
Departure PortCape Town
Destination PortLisbon
Itinerary
Cape Town, Cape Town, Walvis Bay, Walvis Bay, Namibe, Luanda, Sao Tome Island, Cotonou, Tema, Takoradi, Praia, Santiago Island, Praia, Santiago Island, Porto Grande, Santa Cruz de Tenerife, Las Palmas de Gran Canaria, Funchal, Madeira, Funchal, Madeira and Lisbon

From £11,100pp

Plus substantial savings from Deluxe Cruises

14 Nights

Cape Town to Tema

Departure Date
12 Apr 25
Cruise LineCrystal
Cruise TypeOcean
ShipCrystal Symphony
RegionAfrica
Departure PortCape Town
Destination PortTema
Itinerary
Cape Town, Cape Town, Walvis Bay, Walvis Bay, Namibe, Luanda, Sao Tome Island, Cotonou and Tema

From £5,300pp

Plus substantial savings from Deluxe Cruises

8 Nights

Wine Cruise: Captivating Canary Islands

Departure Date
15 Apr 25
Cruise LineWindstar Cruises
Cruise TypeOcean
ShipStar Pride
RegionAfrica
Departure PortSanta Cruz de Tenerife
Destination PortLisbon
Itinerary
Santa Cruz de Tenerife, San Sebastian, Las Palmas, Lanzarote, Lanzarote, Funchal, Madeira, Funchal, Madeira and Lisbon

From £2,051pp

Plus substantial savings from Deluxe Cruises

19 Nights

Skyscrapers & Souks

Departure Date
16 May 25
Cruise LineRegent Seven Seas Cruises
Cruise TypeOcean
ShipSeven Seas Voyager
RegionAfrica
Departure PortDubai
Destination PortCape Town
Itinerary
Dubai, Khasab, Mahé, Mahé, Nosy Bé, Mayotte Island, Maputo, Durban, Durban, Gqeberha (ex Port Elizabeth) and Cape Town

From £10,079pp

Plus substantial savings from Deluxe Cruises

26 Nights

Africa Navigator

Departure Date
22 May 25
Cruise LineOceania Cruises
Cruise TypeOcean
ShipNautica
RegionAfrica
Departure PortCape Town
Destination PortBarcelona
Itinerary
Cape Town, Walvis Bay, Walvis Bay, Luanda, Principe, Lome, Takoradi, Abidjan, Dakar, Mindelo, São Vicente Island, Santa Cruz de La Palma, Puerto del Rosario, Fuerteventura, Agadir, Motril, Alicante and Barcelona

From £7,849pp

Plus substantial savings from Deluxe Cruises

23 Nights

Bold Peaks & Palaces

Departure Date
04 Jun 25
Cruise LineRegent Seven Seas Cruises
Cruise TypeOcean
ShipSeven Seas Voyager
RegionAfrica
Departure PortCape Town
Destination PortLisbon
Itinerary
Cape Town, Walvis Bay, Walvis Bay, Luanda, Principe, Cotonou, Takoradi, Abidjan, Dakar, Porto Grande, Santa Cruz de La Palma, Lisbon and Lisbon

From £7,900pp

Plus substantial savings from Deluxe Cruises

21 Nights

Western Africa Cruise: Senegal, Gambia & Namibia

Departure Date
25 Oct 25
Cruise LineAzamara
Cruise TypeOcean
ShipAzamara Pursuit
RegionAfrica
Departure PortLisbon
Destination PortCape Town
Itinerary
Lisbon, Arrecife, Lanzarote, Las Palmas de Gran Canaria, Dakar, Banjul, Jamestown, Walvis Bay, Walvis Bay, Lüderitz and Cape Town

From £3,199pp

Plus substantial savings from Deluxe Cruises

25 Nights

A Toast To West Africa

Departure Date
31 Oct 25
Cruise LineRegent Seven Seas Cruises
Cruise TypeOcean
ShipSeven Seas Navigator
RegionAfrica
Departure PortBarcelona
Destination PortCape Town
Itinerary
Barcelona, Cádiz, Casablanca, Agadir, Arrecife, Lanzarote, Porto Grande, Dakar, Banjul, Abidjan, Takoradi, Lome, Principe, Walvis Bay, Cape Town and Cape Town

From £11,659pp

Plus substantial savings from Deluxe Cruises

11 Nights

From Lisbon To The Treasures Of The Atlantic

Departure Date
02 Nov 25
Cruise LineHapag-Lloyd Cruises
Cruise TypeOcean
ShipMS EUROPA 2
RegionAfrica
Departure PortLisbon
Destination PortSanta Cruz de La Palma
Itinerary
Lisbon, Lisbon, Agadir, Lanzarote, Puerto del Rosario, Fuerteventura, Las Palmas de Gran Canaria, San Sebastian de la Gomera, Santa Cruz de La Palma, Santa Cruz de Tenerife and Santa Cruz de La Palma

From £5,409pp

Plus substantial savings from Deluxe Cruises

25 Nights

Equatorial Echoes

Departure Date
07 Nov 25
Cruise LineOceania Cruises
Cruise TypeOcean
ShipSirena
RegionAfrica
Departure PortLisbon
Destination PortCape Town
Itinerary
Lisbon, Funchal, Madeira, Santa Cruz de La Palma, Santa Cruz de Tenerife, Mindelo, São Vicente Island, Dakar, Banjul, Abidjan, Takoradi, Lome, Principe, Walvis Bay, Walvis Bay, Cape Town and Cape Town

From £4,582pp

Plus substantial savings from Deluxe Cruises

13 Nights

Africa Cruise: Mauritius, Madagascar & South Africa

Departure Date
15 Nov 25
Cruise LineAzamara
Cruise TypeOcean
ShipAzamara Pursuit
RegionAfrica
Departure PortCape Town
Destination PortPort Louis
Itinerary
Cape Town, Cape Town, Gqeberha (ex Port Elizabeth), Durban, Richards Bay, Tôlanaro, Pointe des Galets, Port Louis and Port Louis

From £4,639pp

Plus substantial savings from Deluxe Cruises

13 Nights

Cape Town to Port Louis

Departure Date
20 Nov 25
Cruise LineThe Ritz-Carlton Yacht Collection
Cruise TypeOcean
ShipLuminara
RegionAfrica
Departure PortCape Town
Destination PortPort Louis
Itinerary
Cape Town, Mossel Bay, Gqeberha (ex Port Elizabeth), Durban, Tuléar, Fort Dauphin (Toalagnaro), Saint-Denis de la Réunion and Port Louis

From £14,900pp

Plus substantial savings from Deluxe Cruises