Africa cruises offer a unique opportunity to explore one of the world's most diverse and fascinating continents. Whether you want to witness the Great Migration of wildebeest and zebras in the Serengeti, explore the ancient ruins of Egypt, or relax on the stunning beaches of South Africa, an Africa cruise has something for everyone. Many cruises also offer opportunities to spot wildlife such as lions, elephants, and giraffes in their natural habitats. With itineraries ranging from a few days to several weeks, there are plenty of options to suit any traveler's preferences and budget. Some cruises even offer exclusive experiences such as hot air balloon rides over the African savanna or visits to remote villages to learn about traditional cultures. Whatever your interests, an Africa cruise promises to be a journey of discovery and adventure.

Africa Itineraries (Page 4)

19 Nights

Majestic Safaris & Modern Spires

Departure Date
25 Nov 25
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Navigator
Region Africa
Departure Port Cape Town
Destination Port Doha
Itinerary
Cape Town, Mossel Bay, Richards Bay, Maputo, Mayotte Island, Nosy Bé, Mahé, Mahé, Muscat, Al Fujayrah, Dubai and Doha

From £7,497pp

Plus substantial savings from Deluxe Cruises

15 Nights

Lisbon to Tema

Departure Date
26 Nov 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Symphony
Region Africa
Departure Port Lisbon
Destination Port Tema
Itinerary
Lisbon, Portimão, Funchal, Madeira, Arrecife, Lanzarote, Santa Cruz de Tenerife, Las Palmas de Gran Canaria, Praia, Santiago Island, Porto Grande and Tema

From £5,800pp

Plus substantial savings from Deluxe Cruises

27 Nights

Lisbon to Cape Town

Departure Date
26 Nov 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Symphony
Region Africa
Departure Port Lisbon
Destination Port Cape Town
Itinerary
Lisbon, Portimão, Funchal, Madeira, Arrecife, Lanzarote, Santa Cruz de Tenerife, Las Palmas de Gran Canaria, Praia, Santiago Island, Porto Grande, Tema, Cotonou, Sao Tome Island, Luanda, Namibe, Walvis Bay and Cape Town

From £8,500pp

Plus substantial savings from Deluxe Cruises

22 Nights

Piraeus (Athens) to Dubai

Departure Date
29 Nov 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Symphony
Region Africa
Departure Port Piraeus
Destination Port Dubai
Itinerary
Piraeus, Piraeus, Alexandria, Port Said, 'Aqaba, 'Aqaba, Luxor, Luxor, Jeddah, Salalah, Muscat, Muscat, Khasab, Abu Dhabi, Dubai and Dubai

From £8,550pp

Plus substantial savings from Deluxe Cruises

18 Nights

18-Night Africa Cruise: Canary Islands, Senegal & Namibia

Departure Date
02 Dec 25
Cruise Line Azamara
Cruise Type Ocean
Ship Azamara Journey
Region Africa
Departure Port Las Palmas de Gran Canaria
Destination Port Cape Town
Itinerary
Las Palmas de Gran Canaria, Dakar, Banjul, Jamestown, Walvis Bay, Walvis Bay, Lüderitz and Cape Town

From £2,799pp

Plus substantial savings from Deluxe Cruises

17 Nights

Safari and The Seychelles Island hopping

Departure Date
11 Dec 25
Cruise Line Emerald Cruises
Cruise Type Ocean
Ship Emerald Azzurra
Region Africa
Departure Port Nairobi
Destination Port Mahé
Itinerary
Nairobi, Nairobi, Samburu National Reserve, Samburu National Reserve, Samburu National Reserve, Lake Nakuru National Park, Lake Nakuru National Park, Masai Mara, Masai Mara, Masai Mara, Masai Mara, Nairobi, Mahé, Mahé, Mahé, Saint Anne, Alderney Island, Saint Anne, Alderney Island, Therese Island, Therese Island, Praslin Island, Cousin Island, Praslin Island, La Digue, La Digue, Curieuse Island, Curieuse Island, Curieuse Island, Aride Island, Mahé and Mahé

From Please Call

Plus substantial savings from Deluxe Cruises

12 Nights

Tema to Cape Town

Departure Date
11 Dec 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Symphony
Region Africa
Departure Port Tema
Destination Port Cape Town
Itinerary
Tema, Cotonou, Sao Tome Island, Luanda, Namibe, Walvis Bay and Cape Town

From £4,600pp

Plus substantial savings from Deluxe Cruises

25 Nights

World Holiday Spectacular

Departure Date
19 Dec 25
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Voyager
Region Africa
Departure Port Barcelona
Destination Port Cape Town
Itinerary
Barcelona, Cádiz, Arrecife, Lanzarote, Santa Cruz de Tenerife, Porto Grande, Dakar, Banjul, Abidjan, Takoradi, Lome, Principe, Walvis Bay, Cape Town and Cape Town

From £9,097pp

Plus substantial savings from Deluxe Cruises

17 Nights

Safari and The Seychelles Island hopping

Departure Date
20 Dec 25
Cruise Line Emerald Cruises
Cruise Type Ocean
Ship Emerald Azzurra
Region Africa
Departure Port Nairobi
Destination Port Mahé
Itinerary
Nairobi, Nairobi, Samburu National Reserve, Samburu National Reserve, Samburu National Reserve, Lake Nakuru National Park, Lake Nakuru National Park, Masai Mara, Masai Mara, Masai Mara, Masai Mara, Nairobi, Mahé, Mahé, Mahé, Saint Anne, Alderney Island, Saint Anne, Alderney Island, Therese Island, Therese Island, Praslin Island, Cousin Island, Praslin Island, La Digue, La Digue, Curieuse Island, Curieuse Island, Curieuse Island, Aride Island, Mahé and Mahé

From Please Call

Plus substantial savings from Deluxe Cruises

15 Nights

15-Night Africa Cruise: Cape Town, Durban & Port Louis

Departure Date
20 Dec 25
Cruise Line Azamara
Cruise Type Ocean
Ship Azamara Journey
Region Africa
Departure Port Cape Town
Destination Port Port Louis
Itinerary
Cape Town, Cape Town, Mossel Bay, Gqeberha (ex Port Elizabeth), Richards Bay, Durban, Durban, Tôlanaro, Pointe des Galets, Port Louis and Port Louis

From £3,089pp

Plus substantial savings from Deluxe Cruises

30 Nights

Spice Route Rendezvous

Departure Date
20 Dec 25
Cruise Line Oceania Cruises
Cruise Type Ocean
Ship Nautica
Region Africa
Departure Port Dubai
Destination Port Cape Town
Itinerary
Dubai, Abu Dhabi, Al Fujayrah, Muscat, Mumbai (ex Bombay), Mumbai (ex Bombay), Mormugao, Goa, Mangalore, Cochin, Male, Mahé, Mahé, Zanzibar, Zanzibar, Nosy Bé, Richards Bay, Gqeberha (ex Port Elizabeth) and Cape Town

From £7,909pp

Plus substantial savings from Deluxe Cruises

12 Nights

Dubai Round Trip

Departure Date
21 Dec 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Symphony
Region Africa
Departure Port Dubai
Destination Port Dubai
Itinerary
Dubai, Sir Bani Yas Island, Manama, Kuwait, Doha, Doha, Muscat, Khor al Fakkan, Dubai, Dubai and Dubai

From £4,700pp

Plus substantial savings from Deluxe Cruises