Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries (Page 10)

7 Nights

Panama Canal, Cartagena, San Blas Islands & More

Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Star Pride
Region South America
Departure Port Fuerte Amador
Destination Port Oranjestad
Itinerary
Fuerte Amador, Bocas del Toro, San Blas Islands, Cartagena, Cartagena and Oranjestad

From £2,572pp

Plus substantial savings from Deluxe Cruises

Departure Date
08 Mar 25
12 Nights

Amazon & Caribbean Adventure

Cruise Line Viking Ocean Cruises
Cruise Type Ocean
Ship Viking Sea
Region South America
Departure Port Manaus
Destination Port San Juan (Puerto Rico)
Itinerary
Manaus, Manaus, Parintins, Santarém, Iles du Salut, Bridgetown, Castries, Saint John's, San Juan (Puerto Rico) and San Juan (Puerto Rico)

From £5,690pp

Plus substantial savings from Deluxe Cruises

Departure Date
09 Mar 25
12 Nights

Argentina & the Chilean Fjords

Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Octantis
Region South America
Departure Port Ushuaia
Destination Port Valparaiso
Itinerary
Ushuaia, Chilean Fjords, Punta Arenas, Chilean Fjords, Chilean Fjords, Puerto Chacabuco and Valparaiso

From £6,995pp

Plus substantial savings from Deluxe Cruises

Departure Date
10 Mar 25
17 Nights

Panama & Scenic South America

Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Polaris
Region South America
Departure Port Valparaiso
Destination Port Fort Lauderdale, Florida
Itinerary
Valparaiso, Iquique, Callao, Manta, Fuerte Amador, Cozumel and Fort Lauderdale, Florida

From £9,995pp

Plus substantial savings from Deluxe Cruises

Departure Date
11 Mar 25
12 Nights

Rhythms of the Brazilian Coastline

Cruise Line Scenic Ocean Cruises
Cruise Type Ocean
Ship Scenic Eclipse
Region South America
Departure Port Buenos Aires
Destination Port Rio de Janeiro
Itinerary
Buenos Aires, Montevideo, Punta del Este, São Francisco do Sul, Pontal do Sul, Ilhabela, Parati, Ilha Grande, Buzios, Rio de Janeiro and Rio de Janeiro

From £7,595pp

Plus substantial savings from Deluxe Cruises

Departure Date
22 Mar 25
14 Nights

San Cristóbal, Galapagos to San Cristóbal, Galapagos

Cruise Line Silversea
Cruise Type Ocean
Ship Silver Origin
Region South America
Departure Port San Cristóbal Island, Galápagos
Destination Port San Cristóbal Island, Galápagos
Itinerary
San Cristóbal Island, Galápagos, Roca León Dormido, Bartolome Island, Santiago Island, Galápagos, Punta Vicente Roca, Isabela Island, Galápagos, Punta Espinoza, Fernandina Island, Galápagos, Caleta Tagus, Elizabeth Bay, Isabela Island, Galápagos, Post Office Bay, Floreana, Galápagos, Champion Island, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Dragon Hill, Santa Cruz Island, Galápagos, Isla Guy Fawkes, Galapagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, San Cristóbal Island, Galápagos, Roca León Dormido, El Barranco, Genovesa Island, Galápagos, Darwin Bay, Genovesa Island, Galápagos, North Seymour Island, Galapagos, Sullivan Bay, Santiago Island, Galápagos, Mangle Point, Fernandina Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Gardner Bay, Española Island, Galápagos, Punta Suarez, Isla Española, Galápagos, San Cristóbal Island, Galápagos, Cerro Brujo, San Cristóbal Island, Galápagos and San Cristóbal Island, Galápagos

From £65,300pp

Plus substantial savings from Deluxe Cruises

Departure Date
22 Mar 25
17 Nights

Panama & Scenic South America

Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Octantis
Region South America
Departure Port Valparaiso
Destination Port Fort Lauderdale, Florida
Itinerary
Valparaiso, Iquique, Callao, Manta, Fuerte Amador, Cozumel and Fort Lauderdale, Florida

From £9,995pp

Plus substantial savings from Deluxe Cruises

Departure Date
22 Mar 25
12 Nights

Beautiful Brazil & Beyond

Cruise Line Oceania Cruises
Cruise Type Ocean
Ship Marina
Region South America
Departure Port Buenos Aires
Destination Port Rio de Janeiro
Itinerary
Buenos Aires, Buenos Aires, Montevideo, Punta del Este, Balneário de Camboriú, São Francisco do Sul, Santos, Parati, Ilha Grande, Buzios, Rio de Janeiro and Rio de Janeiro

From £3,149pp

Plus substantial savings from Deluxe Cruises

Departure Date
24 Mar 25
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Urubamba, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Baltra Island, Galápagos, Punta Pitt, San Cristóbal Island, Galápagos, Punta Suarez, Isla Española, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From Please Call

Plus substantial savings from Deluxe Cruises

Departure Date
28 Mar 25
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Urubamba, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Baltra Island, Galápagos, Punta Pitt, San Cristóbal Island, Galápagos, Punta Suarez, Isla Española, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,750pp

Plus substantial savings from Deluxe Cruises

Departure Date
11 Apr 25
18 Nights

Premiere: America's West Coast With Canada

Cruise Line Hapag-Lloyd Cruises
Cruise Type Ocean
Ship MS EUROPA 2
Region West Coast US and South America
Departure Port Los Angeles, California
Destination Port Los Angeles, California
Itinerary
Los Angeles, California, Los Angeles, California, San Francisco, California, San Francisco, California, San Francisco, California, Astoria, Oregon, Victoria, British Columbia, Vancouver, British Columbia, Nanaimo, British Columbia, Vancouver, British Columbia, Vancouver, British Columbia, Seattle, Washington, Eureka, California, Santa Barbara, California, San Diego, California and Los Angeles, California

From £10,490pp

Plus substantial savings from Deluxe Cruises

Departure Date
13 Apr 25
14 Nights

Peru and the Galapagos Islands

Cruise Line Tauck
Cruise Type Ocean
Ship Isabela II
Region South America
Departure Port Santa Cruz Island, Galápagos
Destination Port Baltra Island, Galápagos
Itinerary
Santa Cruz Island, Galápagos, Lima, Urubamba, Machu Picchu, Machu Picchu, Cusco, Baltra Island, Galápagos, Baltra Island, Galápagos, Punta Pitt, San Cristóbal Island, Galápagos, Punta Suarez, Isla Española, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, El Edén Island, Galápagos, Baltra Island, Galápagos and Baltra Island, Galápagos

From £11,750pp

Plus substantial savings from Deluxe Cruises

Departure Date
25 Apr 25