Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries (Page 20)

22 Nights

Secrets Of The Amazon

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Miami, Florida
Destination Port Miami, Florida
Itinerary
Miami, Florida, Bridgetown, Port-of-Spain, Macapa, Santarém, Boca de Valeria, Manaus, Parintins, Alter do Chão, Macapa, Saint George's, San Juan (Puerto Rico) and Miami, Florida

From £9,249pp

Plus substantial savings from Deluxe Cruises

Departure Date
09 Nov 26
18 Nights

White Sands & Brazillian Sun

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Miami, Florida
Destination Port Rio de Janeiro
Itinerary
Miami, Florida, Charlotte Amalie, Saint John's, Castries, Bridgetown, Devil's Island, Belem, Recife, Maceió, Salvador de Bahia, Buzios and Rio de Janeiro

From £9,689pp

Plus substantial savings from Deluxe Cruises

Departure Date
04 Jan 27
10 Nights

West Coast Retreat

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Grandeur
Region South America
Departure Port Los Angeles, California
Destination Port Los Angeles, California
Itinerary
Los Angeles, California, Cabo San Lucas, La Paz, Mazatlán, Manzanillo, Mexico, Puerto Vallarta and Los Angeles, California

From £5,079pp

Plus substantial savings from Deluxe Cruises

Departure Date
14 Jan 27
11 Nights

Nights Of Samba & Tango

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Rio de Janeiro
Destination Port Buenos Aires
Itinerary
Rio de Janeiro, Buzios, Ilha Grande, Ilhabela, São Francisco do Sul, Porto Belo, Rio Grande, Montevideo, Montevideo and Buenos Aires

From £7,069pp

Plus substantial savings from Deluxe Cruises

Departure Date
22 Jan 27
18 Nights

Colossal Coastlines

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Buenos Aires
Destination Port Buenos Aires
Itinerary
Buenos Aires, Puerto Madryn, Punta Arenas, Punta Arenas, Ushuaia, Port Stanley, Punta del Este, Montevideo and Buenos Aires

From £10,639pp

Plus substantial savings from Deluxe Cruises

Departure Date
02 Feb 27
18 Nights

Antarctic Encounter

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Buenos Aires
Destination Port Callao
Itinerary
Buenos Aires, Port Stanley, Ushuaia, Punta Arenas, Puerto Montt, San Antonio, Callao and Callao

From £10,639pp

Plus substantial savings from Deluxe Cruises

Departure Date
20 Feb 27
14 Nights

Exotic Coasts & Casco Viejo

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Grandeur
Region South America
Departure Port Miami, Florida
Destination Port Panama City
Itinerary
Miami, Florida, Costa Maya, Harvest Caye, Roatán Island, Georgetown, Grand Cayman, Ocho Rios, Puerto Limón, Cartagena, Colón, Panama City and Panama City

From £6,989pp

Plus substantial savings from Deluxe Cruises

Departure Date
23 Feb 27
17 Nights

Fjords & Glaciers of Southern Chile & Patagonia

Cruise Line Scenic Ocean Cruises
Cruise Type Ocean
Ship Scenic Eclipse
Region South America
Departure Port Buenos Aires
Destination Port Buenos Aires
Itinerary
Buenos Aires, Ushuaia, Cape Horn, Chilean Fjords, Aguila Glacier, Magdalena Island, Tuckers Islets, Admiralty Bay, Bequia, Punta Arenas, Puerto Deseado, Isla Pinguino, Punta Piramides, Montevideo and Buenos Aires

From £10,116pp

Plus substantial savings from Deluxe Cruises

Departure Date
28 Feb 27
22 Nights

Journey To The Amazon

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Grandeur
Region South America
Departure Port Panama City
Destination Port Panama City
Itinerary
Panama City, Oranjestad, Port-of-Spain, Macapa, Santarém, Boca de Valeria, Manaus, Parintins, Alter do Chão, Macapa, Saint George's, Willemstad and Panama City

From £8,739pp

Plus substantial savings from Deluxe Cruises

Departure Date
09 Mar 27
16 Nights

Machu Picchu & Mayan Ruins

Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Callao
Destination Port Miami, Florida
Itinerary
Callao, Callao, Salaverry, Guayaquil, Manta, Golfito, Panama City, Puerto Limón, Roatán Island, Harvest Caye, Costa Maya and Miami, Florida

From £8,889pp

Plus substantial savings from Deluxe Cruises

Departure Date
10 Mar 27