Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries (Page 20)

40 Nights

Buenos Aires to Miami Grand Voyage

Departure Date
17 Feb 27
Cruise Line Azamara
Cruise Type Ocean
Ship Azamara Journey
Region South America
Departure Port Buenos Aires
Destination Port Miami, Florida
Itinerary
Buenos Aires, Buenos Aires, Montevideo, Punta del Este, Port Stanley, Antarctic Sound, Antarctic Sound, Antarctic Sound, Ushuaia, Ushuaia, Punta Arenas, Chilean Fjords, Chilean Fjords, Puerto Chacabuco, Puerto Montt, San Antonio, Coquimbo, Iquique, Arica, Pisco, Callao, Callao, Fuerte Amador, Puerto Limón, San Andrés Island, Cozumel and Miami, Florida

From £8,179pp

Plus substantial savings from Deluxe Cruises

16 Nights

Buenos Aires to Valparaiso

Departure Date
17 Feb 27
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Nova
Region South America
Departure Port Buenos Aires
Destination Port Valparaiso
Itinerary
Buenos Aires, Puerto Madryn, Port Stanley, Ushuaia, Ushuaia, Punta Arenas, Chilean Fjords, Puerto Montt, Valparaiso and Valparaiso

From £8,800pp

Plus substantial savings from Deluxe Cruises

18 Nights

Antarctic Encounter

Departure Date
20 Feb 27
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Mariner
Region South America
Departure Port Buenos Aires
Destination Port Callao
Itinerary
Buenos Aires, Port Stanley, Ushuaia, Punta Arenas, Puerto Montt, San Antonio, Callao and Callao

From £10,639pp

Plus substantial savings from Deluxe Cruises

14 Nights

Exotic Coasts & Casco Viejo

Departure Date
23 Feb 27
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Grandeur
Region South America
Departure Port Miami, Florida
Destination Port Panama City
Itinerary
Miami, Florida, Costa Maya, Harvest Caye, Roatán Island, Georgetown, Grand Cayman, Ocho Rios, Puerto Limón, Cartagena, Colón, Panama City and Panama City

From £6,989pp

Plus substantial savings from Deluxe Cruises

17 Nights

South America & the Chilean Fjords

Departure Date
25 Feb 27
Cruise Line Viking Ocean Cruises
Cruise Type Ocean
Ship Viking Jupiter
Region South America
Departure Port Valparaiso
Destination Port Buenos Aires
Itinerary
Valparaiso, Valparaiso, Puerto Montt, Punta Arenas, Ushuaia, Port Stanley, Puerto Madryn, Montevideo, Buenos Aires and Buenos Aires

From £7,995pp

Plus substantial savings from Deluxe Cruises

40 Nights

Antarctic Explorer & the Americas

Departure Date
27 Feb 27
Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Polaris
Region South America
Departure Port Ushuaia
Destination Port Fort Lauderdale, Florida
Itinerary
Ushuaia, Antarctic Experience, Antarctic Experience, Antarctica, Antarctic Experience, Antarctic Experience, Antarctica, Antarctica, Ushuaia, Chilean Fjords, Punta Arenas, Chilean Fjords, Chilean Fjords, Puerto Chacabuco, Valparaiso, Iquique, Callao, Manta, Fuerte Amador, Cozumel and Fort Lauderdale, Florida

From £29,470pp

Plus substantial savings from Deluxe Cruises

17 Nights

Fjords & Glaciers of Southern Chile & Patagonia

Departure Date
28 Feb 27
Cruise Line Scenic Ocean Cruises
Cruise Type Ocean
Ship Scenic Eclipse
Region South America
Departure Port Buenos Aires
Destination Port Buenos Aires
Itinerary
Buenos Aires, Ushuaia, Cape Horn, Chilean Fjords, Aguila Glacier, Magdalena Island, Tuckers Islets, Admiralty Bay, Bequia, Punta Arenas, Puerto Deseado, Isla Pinguino, Punta Piramides, Montevideo and Buenos Aires

From £9,754pp

Plus substantial savings from Deluxe Cruises

19 Nights

19 nights - San Antonio to Fort Lauderdale - February 2027

Departure Date
28 Feb 27
Cruise Line Cunard Line
Cruise Type Ocean
Ship Queen Anne
Region South America
Departure Port San Antonio
Destination Port Fort Lauderdale, Florida
Itinerary
San Antonio, San Antonio, Coquimbo, Arica, Callao, Callao, Manta, Fuerte Amador, Aruba and Fort Lauderdale, Florida

From £2,849pp

Plus substantial savings from Deluxe Cruises

33 Nights

33 nights - San Antonio to Southampton - February 2027

Departure Date
28 Feb 27
Cruise Line Cunard Line
Cruise Type Ocean
Ship Queen Anne
Region South America
Departure Port San Antonio
Destination Port Southampton
Itinerary
San Antonio, San Antonio, Coquimbo, Arica, Callao, Callao, Manta, Fuerte Amador, Aruba, Fort Lauderdale, Florida, Port Canaveral, Florida, Ponta Delgada, Azores and Southampton

From £3,999pp

Plus substantial savings from Deluxe Cruises

36 Nights

36 nights - San Antonio to Hamburg - February 2027

Departure Date
28 Feb 27
Cruise Line Cunard Line
Cruise Type Ocean
Ship Queen Anne
Region South America
Departure Port San Antonio
Destination Port Hamburg
Itinerary
San Antonio, San Antonio, Coquimbo, Arica, Callao, Callao, Manta, Fuerte Amador, Aruba, Fort Lauderdale, Florida, Port Canaveral, Florida, Ponta Delgada, Azores, Southampton, Zeebrugge and Hamburg

From £4,599pp

Plus substantial savings from Deluxe Cruises

18 Nights

Valparaiso to Miami

Departure Date
05 Mar 27
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Nova
Region South America
Departure Port Valparaiso
Destination Port Miami, Florida
Itinerary
Valparaiso, Arica, Callao, Callao, Guayaquil, Panama City, Cozumel and Miami, Florida

From £7,300pp

Plus substantial savings from Deluxe Cruises

22 Nights

Journey To The Amazon

Departure Date
09 Mar 27
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Grandeur
Region South America
Departure Port Panama City
Destination Port Panama City
Itinerary
Panama City, Oranjestad, Port-of-Spain, Macapa, Santarém, Boca de Valeria, Manaus, Parintins, Alter do Chão, Macapa, Saint George's, Willemstad and Panama City

From £9,129pp

Plus substantial savings from Deluxe Cruises