Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries (Page 5)

10 Nights

Buenos Aires to Rio de Janeiro

Departure Date
21 Feb 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Ray
Region South America
Departure Port Buenos Aires
Destination Port Rio de Janeiro
Itinerary
Buenos Aires, Buenos Aires, Montevideo, Punta del Este, Balneário de Camboriú, Ilhabela, Rio de Janeiro, Rio de Janeiro and Rio de Janeiro

From £5,500pp

Plus substantial savings from Deluxe Cruises

46 Nights

Antarctica, Chile & the Americas

Departure Date
21 Feb 25
Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Octantis
Region South America
Departure Port Ushuaia
Destination Port Fort Lauderdale, Florida
Itinerary
Ushuaia, West Point Island, Port Stanley, Antarctic Experience, Antarctica, Antarctic Experience, Antarctic Experience, South Georgia Island, South Georgia Island, South Georgia Island, Antarctic Experience, Ushuaia, Garibaldi Fjord, Alberto de Agostini National Park, Chilean Fjords, Punta Arenas, Chilean Fjords, Chilean Fjords, Puerto Chacabuco, Valparaiso, Iquique, Callao, Manta, Fuerte Amador, Cozumel and Fort Lauderdale, Florida

From £33,395pp

Plus substantial savings from Deluxe Cruises

11 Nights

Buenos Aires to Rio de Janeiro

Departure Date
22 Feb 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Serenity
Region South America
Departure Port Buenos Aires
Destination Port Rio de Janeiro
Itinerary
Buenos Aires, Balneário de Camboriú, São Francisco do Sul, Santos, Santos, Ilhabela, Paraty, Rio De Janeiro, Rio de Janeiro, Rio de Janeiro and Rio de Janeiro

From £5,400pp

Plus substantial savings from Deluxe Cruises

25 Nights

Emerald Reefs & Amazon Adventure

Departure Date
24 Feb 25
Cruise Line Regent Seven Seas Cruises
Cruise Type Ocean
Ship Seven Seas Navigator
Region South America
Departure Port Miami, Florida
Destination Port Miami, Florida
Itinerary
Miami, Florida, Gustavia, Pointe-à-Pitre, Saint George's, Port-of-Spain, Santarém, Boca de Valeria, Manaus, Manaus, Parintins, Alter do Chão, Bridgetown, Roseau, Philipsburg, San Juan (Puerto Rico), Great Stirrup Cay and Miami, Florida

From £13,859pp

Plus substantial savings from Deluxe Cruises

25 Nights

25-Night Carnival Rio & Amazon Voyage

Departure Date
25 Feb 25
Cruise Line Azamara
Cruise Type Ocean
Ship Azamara Journey
Region South America
Departure Port Buenos Aires
Destination Port Bridgetown
Itinerary
Buenos Aires, Buenos Aires, Montevideo, Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Salvador de Bahia, Macapa, Alter do Chão, Manaus, Manaus, Parintins, Santarém, Macapa, Scarborough and Bridgetown

From £3,399pp

Plus substantial savings from Deluxe Cruises

31 Nights

San Antonio to Southampton

Departure Date
25 Feb 25
Cruise Line Cunard Line
Cruise Type Ocean
Ship Queen Victoria
Region South America
Departure Port San Antonio
Destination Port Southampton
Itinerary
San Antonio, Coquimbo, Arica, Callao, Callao, Manta, Aruba, Nassau, Fort Lauderdale, Florida, Freeport, Grand Bahama, Hamilton, Ponta Delgada, Azores and Southampton

From £3,699pp

Plus substantial savings from Deluxe Cruises

17 Nights

San Antonio to Fort Lauderdale

Departure Date
25 Feb 25
Cruise Line Cunard Line
Cruise Type Ocean
Ship Queen Victoria
Region South America
Departure Port San Antonio
Destination Port Fort Lauderdale, Florida
Itinerary
San Antonio, Coquimbo, Arica, Callao, Callao, Manta, Aruba, Nassau and Fort Lauderdale, Florida

From £2,659pp

Plus substantial savings from Deluxe Cruises

12 Nights

Argentina & the Chilean Fjords

Departure Date
27 Feb 25
Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Polaris
Region South America
Departure Port Ushuaia
Destination Port Valparaiso
Itinerary
Ushuaia, Chilean Fjords, Punta Arenas, Chilean Fjords, Chilean Fjords, Puerto Chacabuco and Valparaiso

From £7,145pp

Plus substantial savings from Deluxe Cruises

31 Nights

Antarctica, Argentina & Brazil - Cruise & Land journey

Departure Date
28 Feb 25
Cruise Line Scenic Ocean Cruises
Cruise Type Ocean
Ship Scenic Eclipse
Region South America
Departure Port Buenos Aires
Destination Port Rio de Janeiro
Itinerary
Buenos Aires, Buenos Aires, Ushuaia, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, Antarctic Peninsula, South Georgia Island, South Georgia Island, South Georgia Island, South Georgia Island, Falkland Islands, Falkland Islands, Buenos Aires, Buenos Aires, Buenos Aires, Buenos Aires, Iguazú Falls, Iguazú Falls, Iguazú Falls, Iguazú Falls, Rio de Janeiro, Rio de Janeiro, Rio de Janeiro and Rio de Janeiro

From £31,201pp

Plus substantial savings from Deluxe Cruises

14 Nights

San Cristóbal, Galapagos to San Cristóbal, Galapagos

Departure Date
01 Mar 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Origin
Region South America
Departure Port San Cristóbal Island, Galápagos
Destination Port San Cristóbal Island, Galápagos
Itinerary
San Cristóbal Island, Galápagos, Roca León Dormido, El Barranco, Genovesa Island, Galápagos, Darwin Bay, Genovesa Island, Galápagos, North Seymour Island, Galapagos, Sullivan Bay, Santiago Island, Galápagos, Mangle Point, Fernandina Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Gardner Bay, Española Island, Galápagos, Punta Suarez, Isla Española, Galápagos, San Cristóbal Island, Galápagos, Cerro Brujo, San Cristóbal Island, Galápagos, San Cristóbal Island, Galápagos, San Cristóbal Island, Galápagos, Roca León Dormido, Bartolome Island, Santiago Island, Galápagos, Punta Vicente Roca, Isabela Island, Galápagos, Punta Espinoza, Fernandina Island, Galápagos, Caleta Tagus, Elizabeth Bay, Isabela Island, Galápagos, Post Office Bay, Floreana, Galápagos, Champion Island, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Dragon Hill, Santa Cruz Island, Galápagos, Isla Guy Fawkes, Galapagos, Santa Cruz Island, Galápagos and San Cristóbal Island, Galápagos

From Please Call

Plus substantial savings from Deluxe Cruises

7 Nights

Panama Canal, Cartagena, San Blas Islands & More

Departure Date
01 Mar 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Star Pride
Region South America
Departure Port Oranjestad
Destination Port Fuerte Amador
Itinerary
Oranjestad, Cartagena, Cartagena, San Blas Islands, Bocas del Toro and Fuerte Amador

From £2,735pp

Plus substantial savings from Deluxe Cruises

7 Nights

Monteverde Cloud Forest & Arenal Volcano Cruise Tour

Departure Date
01 Mar 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Wind Star
Region South America
Departure Port Colón
Destination Port Puerto Caldera
Itinerary
Colón, Fuerte Amador, Fuerte Amador, Isla Parida, Golfo Dulce, Quepos (Puerto Quepos) and Puerto Caldera

From £4,933pp

Plus substantial savings from Deluxe Cruises