Cartagena, Colombia

Location

Cartagena's magnificent city walls and fortresses, now a UNESCO World Heritage Site, enclose a well-restored historic center (the Cuidad Amurallada, or walled city) with plazas, churches, museums, and shops that have made it a lively coastal vacation spot for South Americans and others. New hotels and restaurants make the walled city a desirable place to stay, and the formerly down-at-the-heels Getsemaní neighborhood attracts those seeking a bohemian buzz. The historic center is a small section of Cartagena; many hotels are in the Bocagrande district, an elongated peninsula where high-rise hotels overlook a long, gray-sand beach.When it was founded in 1533 by Spanish conquistador Pedro de Heredia, Cartagena was the only port on the South American mainland. Gold and silver looted from indigenous peoples passed through here en route to Spain and attracted pirates, including Sir Francis Drake, who in 1586 torched 200 buildings. Cartagena's walls protected the city's riches as well as the New World's most important African slave market.

Cartagena, Colombia Itineraries

13 Nights

Star Collector: Coffee, Canal & Callaloo: Central America, Colombia & the Caribbean

Departure Date
07 Dec 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Star Pride
Region Caribbean
Departure Port San Juan (Puerto Rico)
Destination Port Puerto Caldera
Itinerary
San Juan (Puerto Rico), Santo Domingo, Cartagena, Cartagena, San Blas Islands, Colón, Fuerte Amador, Fuerte Amador, Isla Parida, Golfo Dulce, Quepos (Puerto Quepos) and Puerto Caldera

From £4,247pp

Plus substantial savings from Deluxe Cruises

6 Nights

The Spanish Main: Rise of the New World

Departure Date
07 Dec 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Star Pride
Region Caribbean
Departure Port San Juan (Puerto Rico)
Destination Port Colón
Itinerary
San Juan (Puerto Rico), Santo Domingo, Cartagena, Cartagena, San Blas Islands and Colón

From £1,383pp

Plus substantial savings from Deluxe Cruises

7 Nights

Bridgetown to Cartagena

Departure Date
07 Dec 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Serenity
Region Caribbean
Departure Port Bridgetown
Destination Port Cartagena
Itinerary
Bridgetown, Saint George's, Kralendijk, Willemstad, Oranjestad and Cartagena

From £3,650pp

Plus substantial savings from Deluxe Cruises

7 Nights

Magic of Colombia

Departure Date
13 Dec 25
Cruise Line Ama Waterways
Cruise Type River
Ship AmaMagdalena
Region Magdalena
Departure Port Barranquilla
Destination Port Cartagena
Itinerary
Barranquilla, Magangué, Santa Cruz de Mompox, Santa Cruz de Mompox, Santa Cruz de Mompox, Pinto, Calamar, Palenque, Cartagena and Cartagena

From £5,722pp

Plus substantial savings from Deluxe Cruises

7 Nights

Enchanting Colombia and Panamanian Islands

Departure Date
13 Dec 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Wind Spirit
Region Panama Canal
Departure Port Colón
Destination Port Oranjestad
Itinerary
Colón, San Blas Islands, Cartagena, Cartagena, Santa Marta and Oranjestad

From £2,450pp

Plus substantial savings from Deluxe Cruises

7 Nights

Enchanting Colombia and Panamanian Islands

Departure Date
13 Dec 25
Cruise Line Windstar Cruises
Cruise Type Ocean
Ship Wind Spirit
Region South America
Departure Port Colón
Destination Port Oranjestad
Itinerary
Colón, San Blas Islands, Cartagena, Cartagena, Oranjestad and Oranjestad

From £1,621pp

Plus substantial savings from Deluxe Cruises

8 Nights

Cartagena to Fort Lauderdale

Departure Date
14 Dec 25
Cruise Line Crystal
Cruise Type Ocean
Ship Crystal Serenity
Region Caribbean
Departure Port Cartagena
Destination Port Fort Lauderdale, Florida
Itinerary
Cartagena, Cartagena, Santo Domingo, Samaná, Grand Turk Island, Freeport, Grand Bahama and Fort Lauderdale, Florida

From £4,300pp

Plus substantial savings from Deluxe Cruises

7 Nights

Wonders of Colombia

Departure Date
17 Dec 25
Cruise Line Ama Waterways
Cruise Type River
Ship AmaMelodia
Region Magdalena
Departure Port Cartagena
Destination Port Barranquilla
Itinerary
Cartagena, Palenque, Calamar, Magangué, Santa Cruz de Mompox, Santa Cruz de Mompox, Santa Cruz de Mompox, Pinto, Barranquilla and Barranquilla

From £5,876pp

Plus substantial savings from Deluxe Cruises

137 Nights

Viking World Cruise 2025-2026

Departure Date
19 Dec 25
Cruise Line Viking Ocean Cruises
Cruise Type Ocean
Ship Viking Sky
Region World-wide
Departure Port Fort Lauderdale, Florida
Destination Port London (Greenwich)
Itinerary
Fort Lauderdale, Florida, Cozumel, Cartagena, Colón, Puntarenas, Acajutla, Los Angeles, California, Honolulu, Hawaii, Honolulu, Hawaii, Vaitape, Papeete, Tahiti, Papeete, Tahiti, Rarotonga, Waitangi, Bay of Islands, Auckland, Tauranga, Napier, Wellington, Sydney, New South Wales, Sydney, New South Wales, Mooloolaba, Queensland, Airlie Beach, Cairns, Queensland, Cairns, Queensland, Darwin, Northern Territory, Rinca Island, Lombok, Benoa, Bali, Benoa, Bali, Semarang, Jakarta, Jakarta, Singapore, Singapore, Port Klang, Langkawi Island, Georgetown, Penang, Phuket, Colombo, Colombo, Male, Victoria, Mahé, Mombasa, Mombasa, Zanzibar, Zanzibar, Hell-Ville, Maputo, Richards Bay, Durban, East London, Gqeberha (ex Port Elizabeth), Cape Town, Cape Town, Lüderitz, Walvis Bay, Walvis Bay, Luanda, Praia, Santiago Island, Mindelo, São Vicente Island, Puerto de la Estaca, Santa Cruz de Tenerife, Canary Islands, Agadir, Agadir, Casablanca, Casablanca, Cádiz, Lisbon, Lisbon, Leixões, La Coruña, Le Havre, Dover, London (Greenwich) and London (Greenwich)

From £87,990pp

Plus substantial savings from Deluxe Cruises

17 Nights

Panama Canal & the Pacific Coast

Departure Date
19 Dec 25
Cruise Line Viking Ocean Cruises
Cruise Type Ocean
Ship Viking Sky
Region Caribbean
Departure Port Fort Lauderdale, Florida
Destination Port Los Angeles, California
Itinerary
Fort Lauderdale, Florida, Cozumel, Cartagena, Colón, Puntarenas, Acajutla and Los Angeles, California

From £6,690pp

Plus substantial savings from Deluxe Cruises

16 Nights

Cartagena to Philipsburg, St. Maarten

Departure Date
19 Dec 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Shadow
Region Caribbean
Departure Port Cartagena
Destination Port Philipsburg
Itinerary
Cartagena, Santa Marta, Oranjestad, Oranjestad, Kralendijk, Willemstad, Castries, Port Elizabeth, Bequia, Bridgetown, Bridgetown, Kingstown, Saint George's, Trois-Ilets, Saint Thomas, Saint John's and Philipsburg

From £6,800pp

Plus substantial savings from Deluxe Cruises

9 Nights

Cartagena to Bridgetown

Departure Date
19 Dec 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Shadow
Region Caribbean
Departure Port Cartagena
Destination Port Bridgetown
Itinerary
Cartagena, Santa Marta, Oranjestad, Oranjestad, Kralendijk, Willemstad, Castries, Port Elizabeth, Bequia and Bridgetown

From £3,360pp

Plus substantial savings from Deluxe Cruises