Embarking on a cruise to South America is a captivating voyage that promises a seamless blend of luxury and exploration. These cruises allow travelers to navigate the continent's diverse coastal wonders, offering a unique perspective on its iconic landmarks and hidden gems. Whether sailing along the Brazilian coast with its lively beach cities, exploring the fjords of Chile and Argentina, or navigating the historic waters around the Galápagos Islands, each itinerary is carefully curated to showcase the best of South America. Onboard amenities and curated shore excursions provide passengers with opportunities to immerse themselves in local cultures, savor exotic cuisines, and witness the natural beauty that defines this extraordinary part of the world. With the comfort of a floating sanctuary and the thrill of discovering new landscapes each day, a cruise to South America is a voyage that promises to create indelible memories for every traveler.

South America Itineraries (Page 9)

14 Nights

San Cristóbal, Galapagos to San Cristóbal, Galapagos

Departure Date
18 Oct 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Origin
Region South America
Departure Port San Cristóbal Island, Galápagos
Destination Port San Cristóbal Island, Galápagos
Itinerary
San Cristóbal Island, Galápagos, Roca León Dormido, Bartolome Island, Santiago Island, Galápagos, Punta Vicente Roca, Isabela Island, Galápagos, Punta Espinoza, Fernandina Island, Galápagos, Caleta Tagus, Elizabeth Bay, Isabela Island, Galápagos, Post Office Bay, Floreana, Galápagos, Champion Island, Galápagos, Punta Cormorant, Floreana Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Los Gemelos, Santa Cruz Island, Galápagos, Dragon Hill, Santa Cruz Island, Galápagos, Isla Guy Fawkes, Galapagos, Santa Cruz Island, Galápagos, San Cristóbal Island, Galápagos, Roca León Dormido, San Cristóbal Island, Galápagos, El Barranco, Genovesa Island, Galápagos, Darwin Bay, Genovesa Island, Galápagos, North Seymour Island, Galapagos, Sullivan Bay, Santiago Island, Galápagos, Mangle Point, Fernandina Island, Galápagos, Punta Moreno, Isabella Island, Galapagos, Los Gemelos, Santa Cruz Island, Galápagos, Puerto Ayora, Isla Santa Cruz, Gardner Bay, Española Island, Galápagos, Punta Suarez, Isla Española, Galápagos, San Cristóbal Island, Galápagos, Cerro Brujo, San Cristóbal Island, Galápagos and San Cristóbal Island, Galápagos

From £19,900pp

Plus substantial savings from Deluxe Cruises

9 Nights

9-Day Heart Of The Amazon

Departure Date
21 Oct 25
Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Belem
Destination Port Belem
Itinerary
Belem, Macapa, Amazon Experience, Amazon Experience, Santarém, Amazon Experience, Amazon Experience, Amazon Experience, Macapa and Belem

From £4,466pp

Plus substantial savings from Deluxe Cruises

21 Nights

21-Day The Complete Amazon Experience & Coast Of Brazil

Departure Date
21 Oct 25
Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Belem
Destination Port Rio de Janeiro
Itinerary
Belem, Macapa, Amazon Experience, Amazon Experience, Santarém, Amazon Experience, Amazon Experience, Amazon Experience, Macapa, Belem, Macapa, Amazon Experience, Amazon Experience, Amazon Experience, Macapa, Salvador de Bahia and Rio de Janeiro

From £9,531pp

Plus substantial savings from Deluxe Cruises

12 Nights

Chilean Fjords & Scenic Shores

Departure Date
23 Oct 25
Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Polaris
Region South America
Departure Port Valparaiso
Destination Port Ushuaia
Itinerary
Valparaiso, Puerto Chacabuco, Chilean Fjords, Chilean Fjords, Punta Arenas, Chilean Fjords and Ushuaia

From £7,995pp

Plus substantial savings from Deluxe Cruises

12 Nights

12-Day Amazon Delta & Coast Of Brazil

Departure Date
30 Oct 25
Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Belem
Destination Port Rio de Janeiro
Itinerary
Belem, Macapa, Amazon Experience, Amazon Experience, Amazon Experience, Macapa, Salvador de Bahia and Rio de Janeiro

From £6,462pp

Plus substantial savings from Deluxe Cruises

40 Nights

40-Day From The Amazon To South Georgia & The Antarctic

Departure Date
30 Oct 25
Cruise Line Seabourn
Cruise Type Ocean
Ship Seabourn Venture
Region South America
Departure Port Belem
Destination Port Ushuaia
Itinerary
Belem, Macapa, Amazon Experience, Amazon Experience, Amazon Experience, Macapa, Salvador de Bahia, Rio de Janeiro, Parati, Camboriú, Montevideo, Falkland Islands, Falkland Islands, Port Stanley, South Georgia Experience, South Georgia Experience, South Georgia Experience, South Georgia Experience, South Georgia Experience, Antarctic Experience, Antarctic Experience, Antarctic Experience, Antarctic Experience, Antarctic Experience, Antarctic Experience, Ushuaia and Buenos Aires

From £22,254pp

Plus substantial savings from Deluxe Cruises

12 Nights

Chilean Fjords & Scenic Shores

Departure Date
30 Oct 25
Cruise Line Viking Ocean Cruises
Cruise Type
Ship Viking Octantis
Region South America
Departure Port Valparaiso
Destination Port Ushuaia
Itinerary
Valparaiso, Puerto Chacabuco, Chilean Fjords, Chilean Fjords, Punta Arenas, Chilean Fjords and Ushuaia

From £7,995pp

Plus substantial savings from Deluxe Cruises

14 Nights

San Cristóbal, Galapagos to San Cristóbal, Galapagos

Departure Date
01 Nov 25
Cruise Line Silversea
Cruise Type Ocean
Ship Silver Origin
Region South America
Departure Port San Cristóbal Island, Galápagos
Destination Port San Cristóbal Island, Galápagos
Itinerary

From £18,200pp

Plus substantial savings from Deluxe Cruises

11 Nights

Expedition Central America With Panama Canal - The Beauty Of The Panama Canal

Departure Date
08 Nov 25
Cruise Line Hapag-Lloyd Cruises
Cruise Type Ocean
Ship Hanseatic Inspiration
Region South America
Departure Port Panama City
Destination Port Colón
Itinerary
Panama City, Quepos (Puerto Quepos), Isla Iguana, Colón and Colón

From £5,667pp

Plus substantial savings from Deluxe Cruises

25 Nights

Call Of The Amazon

Departure Date
12 Nov 25
Cruise Line Oceania Cruises
Cruise Type Ocean
Ship Insignia
Region South America
Departure Port Miami, Florida
Destination Port Miami, Florida
Itinerary
Miami, Florida, Saint John's, Castries, Saint George's, Scarborough, Santarém, Boca de Valeria, Manaus, Manaus, Parintins, Alter do Chão, Bridgetown, Roseau, Philipsburg, San Juan (Puerto Rico) and Miami, Florida

From £5,039pp

Plus substantial savings from Deluxe Cruises

16 Nights

Expedition South America With Panama Canal - Mysterious Equatorial Adventure

Departure Date
19 Nov 25
Cruise Line Hapag-Lloyd Cruises
Cruise Type Ocean
Ship Hanseatic Inspiration
Region West Coast US, South America and Panama Canal
Departure Port Colón
Destination Port Valparaiso
Itinerary
Colón, San Miguel Bay, Punta Alegre, Utría National Park, Isla de la Plata, Salaverry, Callao, Paracas, Isla Pan de Azúcar and Valparaiso

From £8,247pp

Plus substantial savings from Deluxe Cruises

17 Nights

South America & the Chilean Fjords

Departure Date
29 Nov 25
Cruise Line Viking Ocean Cruises
Cruise Type Ocean
Ship Viking Jupiter
Region South America
Departure Port Buenos Aires
Destination Port Valparaiso
Itinerary
Buenos Aires, Buenos Aires, Montevideo, Puerto Madryn, Port Stanley, Ushuaia, Punta Arenas, Puerto Montt, Valparaiso and Valparaiso

From £6,790pp

Plus substantial savings from Deluxe Cruises